Glucose Tolerance Test (GTT), 2hr, 75g
CPT Code(s):
82947, 82950
Turnaround Time:
8 hours
Specimen Requirements
Preferred Specimen:
Serum
Minimum Volume:
1.0 mL
Transport Container:
Serum Separator Tube (SST) or Red Top Tube
Transport Temperature:
Room Temperature
Collection Instructions:
Collect first fasting specimen before adminstering 75 gram Glucola. Draw second specimen 2 hours post Glucola. Allow blood to clot completely prior to centrifugation. Separate serum from cells within 45 minutes of collection.
Rejection Criteria:
Gross hemolysis; lipemia; improper labeling
Stability Criteria
Room Temperature:
8 hours
Refrigerated:
72 hours
Frozen:
30 days
Clinical Significance
The Glucose Tolerance, 2 hr PP 75g Glucola holds specific clinical significance and diagnostic use in evaluating glucose metabolism and diagnosing gestational diabetes mellitus (GDM). It is a specific variant of the glucose tolerance test performed during pregnancy.
The specific clinical significance and diagnostic use of the Glucose Tolerance, 2 hr PP 75g Glucola include:
1. Gestational Diabetes Diagnosis: The test is primarily used to screen and diagnose gestational diabetes mellitus (GDM). GDM refers to the development of high blood glucose levels during pregnancy, which can pose risks for both the mother and the baby. The test involves administering a 75g oral glucose solution to the patient and measuring blood glucose levels 2 hours after consumption. Elevated glucose levels at this time point suggest impaired glucose tolerance and may indicate the presence of GDM.
2. Assessing Glucose Metabolism: The Glucose Tolerance, 2 hr PP 75g Glucola provides a comprehensive assessment of glucose metabolism during pregnancy. It evaluates the body's ability to handle a significant glucose load and reflects how well insulin is utilized to regulate blood glucose levels. The test helps identify women with impaired glucose tolerance or overt diabetes during pregnancy, allowing for appropriate management and monitoring.
3. Treatment Planning and Pregnancy Management: The test results guide treatment planning and management strategies for women diagnosed with GDM. Early detection and intervention are crucial to prevent complications for both the mother and the baby. Women with GDM may require dietary modifications, exercise recommendations, and, in some cases, medication or insulin therapy to maintain blood glucose levels within a safe range. The Glucose Tolerance, 2 hr PP 75g Glucola helps determine the severity of glucose intolerance and guides individualized treatment plans.
4. Monitoring Pregnancy Outcomes: The test is useful for monitoring the effectiveness of interventions and assessing the impact on pregnancy outcomes. Regular follow-up measurements of blood glucose levels allow healthcare providers to evaluate the response to treatment and make any necessary adjustments. Close monitoring of blood glucose levels during pregnancy helps reduce the risk of complications such as macrosomia (large baby), birth injuries, preeclampsia, and cesarean delivery.
5. Risk Assessment for Future Diabetes: Women diagnosed with GDM are at increased risk of developing type 2 diabetes later in life. The Glucose Tolerance, 2 hr PP 75g Glucola helps identify individuals with gestational diabetes who may require long-term monitoring and lifestyle interventions to prevent or delay the onset of type 2 diabetes.
It is important to note that the interpretation of test results should consider the specific diagnostic criteria and guidelines used by healthcare providers or institutions. Additionally, the Glucose Tolerance, 2 hr PP 75g Glucola is typically performed between 24 and 28 weeks of gestation, but the timing may vary based on individual risk factors and clinical judgment.
In summary, the Glucose Tolerance, 2 hr PP 75g Glucola has specific clinical significance in diagnosing gestational diabetes mellitus, assessing glucose metabolism during pregnancy, guiding treatment plans and pregnancy management, monitoring pregnancy outcomes, and identifying individuals at risk for future diabetes. By evaluating blood glucose levels following the administration of a glucose solution, this test provides valuable information for clinical decision-making, optimizing maternal and fetal health, and improving pregnancy outcomes.