Mycoplasma Genitalium

CPT Code(s):
87563

Turnaround Time:
8 hours

Specimen Requirements

Preferred Specimen:
Urine

Minimum Volume:
1 swab

Transport Container:
PCR Media Uni Swab Sample Kit

Transport Temperature:
Room Temperature

Collection Instructions:
First void urine specimens kept at 2�30 �C must be transferred from the collection cup to the PCR Tube within 4 hours of collection, or within 24 hours when stored at 2�8 �C.

Rejection Criteria:
Specimen received in preservative other than PCR Media Uni Swab kit

Stability Criteria

Room Temperature:
12 months

Refrigerated:
12 months

Frozen:
Unacceptable

Clinical Significance

Mycoplasma Genitalium holds specific clinical significance and diagnostic use in the detection of Mycoplasma genitalium, a sexually transmitted bacterium, in patients. Here are the key points regarding its clinical significance:

1. Diagnosis of Mycoplasma Genitalium Infection: Mycoplasma genitalium is used to diagnose Mycoplasma genitalium infection in individuals, particularly those with symptoms such as urethritis (inflammation of the urethra), cervicitis (inflammation of the cervix), or pelvic inflammatory disease (PID). It is especially relevant when other common sexually transmitted infections, such as chlamydia and gonorrhea, have been ruled out.

2. Identification of Antibiotic Resistance: Mycoplasma genitalium has developed resistance to certain antibiotics commonly used to treat other sexually transmitted infections. Mycoplasma genitalium can provide information on the antibiotic susceptibility of the bacterium, guiding healthcare providers in selecting the most effective treatment.

3. Management of Sexual Partners: Testing for Mycoplasma genitalium is crucial for the management and treatment of sexual partners. If one partner tests positive for Mycoplasma genitalium, it is important to screen and treat their sexual partners to prevent reinfection and reduce the spread of the bacterium.

4. Monitoring Treatment Response: Mycoplasma genitalium can be used to monitor the effectiveness of treatment. Follow-up testing after completion of treatment helps to confirm clearance of the infection and ensure successful therapy.

5. Prevention of Complications: Timely detection and treatment of Mycoplasma genitalium infection can help prevent complications such as infertility, chronic pelvic pain, and increased susceptibility to other sexually transmitted infections.

6. Guidance for Public Health Strategies: Data obtained from Mycoplasma genitalium testing contributes to the understanding of the prevalence, distribution, and antimicrobial resistance patterns of the bacterium. This information is valuable for public health officials in developing effective strategies for prevention, control, and treatment of Mycoplasma genitalium infections.

It is important to note that Mycoplasma genitalium requires specialized laboratory techniques, and not all healthcare facilities may offer it as a routine screening test. Healthcare providers may consider testing for Mycoplasma genitalium in individuals at high risk or those with persistent or recurrent symptoms despite previous treatment for other sexually transmitted infections. Prompt and accurate diagnosis of Mycoplasma genitalium infection enables appropriate management and reduces the potential for complications.