Thyroid Panel
CPT Code(s):
84481, 84439, 84443
Turnaround Time:
8 hours
Specimen Requirements
Preferred Specimen:
Serum
Minimum Volume:
1.0 mL
Transport Container:
Serum Separator Tube (SST) or Red Top Tube
Transport Temperature:
Room Temperature
Collection Instructions:
Allow blood to clot completely prior to centrifugation. Separate serum from cells within 45 minutes of collection.
Rejection Criteria:
Plasma specimen; gross hemolysis; lipemia; improper labeling
Stability Criteria
Room Temperature:
5 days
Refrigerated:
7 days
Frozen:
30 days
Clinical Significance
Thyroid Profile is a comprehensive panel of bloods used to evaluate the function of the thyroid gland. It includes measurements of various thyroid hormones and related markers. This test has specific clinical significance and diagnostic use in the following ways:
1. Assessing Thyroid Function: Thyroid Profile measures the levels of thyroid-stimulating hormone (TSH), free thyroxine (FT4), and triiodothyronine (T3). These hormones play a crucial role in regulating the body's metabolism, energy production, and growth. Abnormal levels of these hormones can indicate an underactive or overactive thyroid gland, helping diagnose conditions such as hypothyroidism or hyperthyroidism.
2. Diagnosing Specific Thyroid Disorders: Thyroid Profile aids in the diagnosis of specific thyroid disorders, including Graves' disease and Hashimoto's thyroiditis. Graves' disease is characterized by overproduction of thyroid hormones, while Hashimoto's thyroiditis is an autoimmune condition causing decreased thyroid hormone production. The test results, along with clinical symptoms and additional diagnostic evaluations, help healthcare providers make accurate diagnoses and develop appropriate treatment plans.
3. Monitoring Thyroid Replacement Therapy: For individuals undergoing thyroid hormone replacement therapy, regular monitoring of thyroid hormone levels is crucial. Thyroid Profile helps healthcare providers assess the effectiveness of the treatment by measuring TSH, FT4, and sometimes T3 levels. Adjustments in medication dosage can be made based on the test results to maintain optimal hormone levels and manage the patient's condition effectively.
4. Evaluating Thyroid Nodules or Goiter: Thyroid nodules are abnormal growths within the thyroid gland, and a goiter refers to an enlarged thyroid gland. Thyroid Profile, along with imaging studies, can provide valuable information in evaluating thyroid nodules and goiter. It helps assess thyroid function, determine if the nodule is autonomously functioning (producing hormones independently), and guide further diagnostic procedures if needed.
5. Monitoring Pregnancy and Fertility: Thyroid hormone levels are important for a healthy pregnancy and normal fetal development. Abnormal thyroid function during pregnancy can lead to complications such as miscarriage, preterm birth, or developmental issues. Thyroid Profile helps monitor thyroid function in pregnant women and guides appropriate interventions to maintain optimal hormone levels for the well-being of both the mother and the baby.
In summary, Thyroid Profile is a valuable tool in assessing thyroid function and diagnosing various thyroid disorders. It helps evaluate thyroid hormone levels, diagnose conditions like hypothyroidism and hyperthyroidism, monitor thyroid replacement therapy, evaluate thyroid nodules or goiter, and monitor thyroid function during pregnancy. The test results, along with clinical evaluation and additional diagnostic tests, provide critical information for healthcare providers in managing thyroid disorders and optimizing patient care.