Tianeptine, Confirmation
CPT Code(s):
80335
Turnaround Time:
48 hours
Specimen Requirements
Preferred Specimen:
Urine
Minimum Volume:
1.0 mL
Transport Container:
Yellow Top Urine Tube
Transport Temperature:
Refrigerated
Collection Instructions:
Random urine
Rejection Criteria:
Specimen received in grossly leaking transport container; specimen received in expired transport media or incorrect transport device; inappropriate specimen transport conditions; specimen received after prolonged delay in transport (usually more than 72 hours); unlabeled specimen or name discrepancy between specimen and request label
Stability Criteria
Room Temperature:
24 hours
Refrigerated:
7 days
Frozen:
30 days
Clinical Significance
Tianeptine is an atypical antidepressant primarily used for the treatment of major depressive disorder (MDD). It has unique pharmacological properties and mechanisms of action compared to other antidepressants. The clinical significance of detecting tianeptine in urine can be understood from several perspectives:
1.Therapeutic Monitoring
Dosage Compliance: Detecting tianeptine in urine can help ensure that patients are adhering to their prescribed medication regimen.
Efficacy Evaluation: Monitoring the presence and concentration of tianeptine in urine may assist healthcare providers in evaluating the drug’s effectiveness and adjusting dosages accordingly.
2. Substance Abuse and Misuse
Abuse Potential: Tianeptine has a potential for abuse, particularly at doses higher than those typically prescribed for depression. It can produce opioid-like effects, leading to its misuse.
Screening and Diagnosis: Urine tests can help identify individuals who may be misusing tianeptine, either alone or in combination with other substances.
3. Toxicology and Overdose
Overdose Detection: High concentrations of tianeptine in urine can indicate an overdose, which requires immediate medical attention due to the risk of severe side effects, including respiratory depression and cardiovascular issues.
Toxicological Studies: Analyzing urine for tianeptine can be part of toxicological assessments in cases of suspected poisoning or adverse drug reactions.
4. Pharmacokinetics and Drug Interactions
Metabolism and Excretion: Understanding the pharmacokinetics of tianeptine, including its metabolism and excretion patterns, is important for optimizing therapeutic regimens.
Drug Interaction Monitoring: Detecting tianeptine and its metabolites in urine can provide insights into potential drug interactions, particularly with other substances that may affect its metabolism.
In conclusion, detecting tianeptine in urine is clinically significant for monitoring therapeutic compliance, identifying misuse, managing overdose situations, understanding pharmacokinetics, and supporting research endeavors.
CPT Code(s):
80335
Turnaround Time:
48 hours
Specimen Requirements
Preferred Specimen:
Urine
Minimum Volume:
1.0 mL
Transport Container:
Yellow Top Urine Tube
Transport Temperature:
Refrigerated
Collection Instructions:
Random urine
Rejection Criteria:
Specimen received in grossly leaking transport container; specimen received in expired transport media or incorrect transport device; inappropriate specimen transport conditions; specimen received after prolonged delay in transport (usually more than 72 hours); unlabeled specimen or name discrepancy between specimen and request label
Stability Criteria
Room Temperature:
24 hours
Refrigerated:
7 days
Frozen:
30 days
Clinical Significance
Tianeptine is an atypical antidepressant primarily used for the treatment of major depressive disorder (MDD). It has unique pharmacological properties and mechanisms of action compared to other antidepressants. The clinical significance of detecting tianeptine in urine can be understood from several perspectives:
1.Therapeutic Monitoring
Dosage Compliance: Detecting tianeptine in urine can help ensure that patients are adhering to their prescribed medication regimen.
Efficacy Evaluation: Monitoring the presence and concentration of tianeptine in urine may assist healthcare providers in evaluating the drug’s effectiveness and adjusting dosages accordingly.
2. Substance Abuse and Misuse
Abuse Potential: Tianeptine has a potential for abuse, particularly at doses higher than those typically prescribed for depression. It can produce opioid-like effects, leading to its misuse.
Screening and Diagnosis: Urine tests can help identify individuals who may be misusing tianeptine, either alone or in combination with other substances.
3. Toxicology and Overdose
Overdose Detection: High concentrations of tianeptine in urine can indicate an overdose, which requires immediate medical attention due to the risk of severe side effects, including respiratory depression and cardiovascular issues.
Toxicological Studies: Analyzing urine for tianeptine can be part of toxicological assessments in cases of suspected poisoning or adverse drug reactions.
4. Pharmacokinetics and Drug Interactions
Metabolism and Excretion: Understanding the pharmacokinetics of tianeptine, including its metabolism and excretion patterns, is important for optimizing therapeutic regimens.
Drug Interaction Monitoring: Detecting tianeptine and its metabolites in urine can provide insights into potential drug interactions, particularly with other substances that may affect its metabolism.
In conclusion, detecting tianeptine in urine is clinically significant for monitoring therapeutic compliance, identifying misuse, managing overdose situations, understanding pharmacokinetics, and supporting research endeavors.
CPT Code(s):
80335
Turnaround Time:
48 hours
Specimen Requirements
Preferred Specimen:
Urine
Minimum Volume:
1.0 mL
Transport Container:
Yellow Top Urine Tube
Transport Temperature:
Refrigerated
Collection Instructions:
Random urine
Rejection Criteria:
Specimen received in grossly leaking transport container; specimen received in expired transport media or incorrect transport device; inappropriate specimen transport conditions; specimen received after prolonged delay in transport (usually more than 72 hours); unlabeled specimen or name discrepancy between specimen and request label
Stability Criteria
Room Temperature:
24 hours
Refrigerated:
7 days
Frozen:
30 days
Clinical Significance
Tianeptine is an atypical antidepressant primarily used for the treatment of major depressive disorder (MDD). It has unique pharmacological properties and mechanisms of action compared to other antidepressants. The clinical significance of detecting tianeptine in urine can be understood from several perspectives:
1.Therapeutic Monitoring
Dosage Compliance: Detecting tianeptine in urine can help ensure that patients are adhering to their prescribed medication regimen.
Efficacy Evaluation: Monitoring the presence and concentration of tianeptine in urine may assist healthcare providers in evaluating the drug’s effectiveness and adjusting dosages accordingly.
2. Substance Abuse and Misuse
Abuse Potential: Tianeptine has a potential for abuse, particularly at doses higher than those typically prescribed for depression. It can produce opioid-like effects, leading to its misuse.
Screening and Diagnosis: Urine tests can help identify individuals who may be misusing tianeptine, either alone or in combination with other substances.
3. Toxicology and Overdose
Overdose Detection: High concentrations of tianeptine in urine can indicate an overdose, which requires immediate medical attention due to the risk of severe side effects, including respiratory depression and cardiovascular issues.
Toxicological Studies: Analyzing urine for tianeptine can be part of toxicological assessments in cases of suspected poisoning or adverse drug reactions.
4. Pharmacokinetics and Drug Interactions
Metabolism and Excretion: Understanding the pharmacokinetics of tianeptine, including its metabolism and excretion patterns, is important for optimizing therapeutic regimens.
Drug Interaction Monitoring: Detecting tianeptine and its metabolites in urine can provide insights into potential drug interactions, particularly with other substances that may affect its metabolism.
In conclusion, detecting tianeptine in urine is clinically significant for monitoring therapeutic compliance, identifying misuse, managing overdose situations, understanding pharmacokinetics, and supporting research endeavors.