WBC, Automated

CPT Code(s):
85048

Turnaround Time:
4 hours

Specimen Requirements

Preferred Specimen:
Whole Blood

Minimum Volume:
1.5mL

Transport Container:
Lavender Top Tube (EDTA)

Transport Temperature:
Room Temperature

Collection Instructions:
Whole blood collected in lavender EDTA tube; inverted several times to mix blood with anticoagulant.

Rejection Criteria:
Hemolysis; clotted specimen; specimen drawn in any anticoagulant other than EDTA; specimen diluted or contaminated with IV fluid; tube not filled with minimum volume; improper labeling; transfer tubes with whole blood; specimen received with plasma removed (plasma is used for other testing)

Stability Criteria

Room Temperature:
24 hours

Refrigerated:
48 hours

Frozen:
Unacceptable

Clinical Significance

The White Blood Cell (WBC) Count test holds specific clinical significance and diagnostic use in assessing a patient's immune system function and detecting various diseases. Here are key points regarding its clinical significance:

1. Immune System Evaluation: WBC Count is used to evaluate the body's immune system response by measuring the number of white blood cells present in the blood. White blood cells play a critical role in fighting off infections and foreign substances. Abnormal WBC counts can indicate an immune system dysfunction, such as an infection or an underlying medical condition.

2. Infection Detection: An elevated WBC count, known as leukocytosis, can be an indication of an ongoing infection. The test helps healthcare providers determine the severity and nature of the infection. Additionally, specific types of white blood cells, such as neutrophils or lymphocytes, can provide insights into the type of infection, helping guide appropriate treatment.

3. Monitoring Treatment Response: WBC Count is useful in monitoring the effectiveness of treatment for infections or immune-related conditions. Changes in the WBC count over time can indicate if the body is responding well to treatment or if further intervention is required.

4. Diagnosis of Blood Disorders: Abnormal WBC counts can also be an indicator of certain blood disorders, such as leukemia or lymphoma. A low WBC count, known as leukopenia, can suggest bone marrow dysfunction or immune system suppression. Conversely, a high WBC count can point to an overproduction of white blood cells, indicating a potential blood disorder.

5. Overall Health Assessment: WBC Count is often included as part of a complete blood count (CBC), which provides a comprehensive evaluation of the patient's overall health. It allows healthcare providers to assess the balance of different types of white blood cells, including neutrophils, lymphocytes, monocytes, eosinophils, and basophils. An imbalance in these cell types can provide valuable information about underlying conditions or diseases.

In summary, WBC Count is essential in evaluating immune system function, detecting infections, monitoring treatment response, diagnosing blood disorders, and providing a comprehensive assessment of overall health. It aids healthcare providers in diagnosing and managing various conditions, guiding appropriate treatment, and promoting better patient outcomes.